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When, by executive decree, all the canine pets of Megasaki City are exiled to a vast garbage-dump called Trash Island, 12-year-old Atari sets off alone in a miniature Junior-Turbo Prop and flies across the river in search of his bodyguard-dog, Spots. There, with the assistance of a pack of newly-found mongrel friends, he begins an epic journey that will decide the fate and future of the entire Prefecture.

The beautifully stop-motion animated Isle of Dogs finds Wes Anderson at his detail-oriented best while telling one of the director's most winsomely charming stories. The voice cast includes Bryan Cranston, Edward Norton, Liev Schreiber, Bill Murray, Scarlett Johansson, Tilda Swinton, Bob Balaban, Greta Gerwig, and Yoko Ono.